Biological Activities of Methanolic Extract of Aegle marmelos against HN Protein of Newcastle Disease Virus

The current study explores the methanolic extracts of leaves and fruit Aegle marmelos (Bael) for their total phenolic content (TPC), flavonoids (TFC), antioxidants, antibiofilms, as well its in ovo antiviral potential against Newcastle disease virus (NDV). drug-likeliness thereof identification an interaction—their molecular docking ligands with target proteins by GOLD—was determined silico using Swiss ADME software. (TFC) was 135.17 ± 2.02 111.2 3.67 mg QE/g, while phenolics (TPC) 185.02 2.15 171.13 6.73 GAE/g, extracts, respectively. In a DPPH assay, IC50 value 63.52 1.48 52.06 1.62. ?g/mL d.w. extract A. showed significantly higher reducing power (i.e., 59.32 0.05 µmol/g d.w) than (p < 0.05). biofilm-inhibition activity 65.78 0.65 µg/mL. Both parts plant potent at concentrations. A silico, three compounds, good interaction HN protein, considerable binding affinities fulfilled parameters. This work shows that phytoconstituents can be used remedy NDV.